New Publication in Allergy: From Disease Control to Disease Modification – The Atopic Dermatitis Disease Activity Index

03. September 2025

“New and advanced treatments for atopic dermatitis (AD) are moving beyond just managing symptoms. For some patients, these therapies can modify the disease itself, potentially leading to long-term remission (“deep remission”) even after stopping medication. This new treatment goal is called “disease modification.” The aim is to fundamentally change the course of AD and its related health conditions, offering transformative and lasting relief. However, optimal measurement of deep remission remains a key challenge for clinicians, researchers, regulators, and ultimately the payers. Our recent publication in Allergy discussing the Atopic Dermatitis Disease Activity Index (ADDAI), a composite tool to help determine if a treatment has successfully achieved true disease modification, helping doctors and patients know if the right treatment approach has been found. (link to publication).

From Disease Control to Disease Modification: The AtopicDermatitis Disease Activity Index

5th Global Allergy Forum in Davos: Allergy and Environment in Focus

31. October 2025

From October 16–18, 2025, more than 70 international experts gathered at the Medicine Campus Davos for the 5th Global Allergy Forum. Under the theme “Allergy and Environment – Loss of Balance and Ways to Restore It”, participants explored how environmental factors drive the rise of allergic diseases and discussed innovative strategies to restore immune balance. Key topics included nutrition and environmental exposures, the role of skin and mucosal barriers, psychoneuroimmunology, and the use of artificial intelligence in allergy research. The forum’s conclusions will be summarized in the upcoming “Davos Declaration.”

More here

New Study Published in Nutrients: Diet Diversity and Adherence to a Mediterranean Diet Pattern in Pregnancy Is Protective Against the Development of Early-Childhood Atopic Dermatitis

18. July 2025

We are proud to share our latest paper published in Nutrients by the CK-CARE Consortium:

read study

This study, conducted within the CARE birth cohort, provides new insights into how maternal nutrition during pregnancy influences the development of atopic dermatitis in early childhood.

Key findings:

A Mediterranean diet during pregnancy significantly reduces the risk of early childhood AD.
Greater dietary diversity is also associated with a lower AD risk.
In contrast, frequent red meat consumption correlates with persistent AD symptoms.

These results underscore the importance of nutritional patterns—not just individual nutrients—in shaping immune development and allergic disease susceptibility.

Congratulations to the research team as well as all members of the CK-CARE study group and our international collaborators.

At CK-CARE, we are committed to advancing prevention strategies for allergic diseases through interdisciplinary and translational research. This study highlights the critical window of opportunity during pregnancy for long-term immune health.

Peter Schmid-Grendelmeier received the EAACI Clinical Fellow Award 2025

2. July 2025

On June 13, 2025, at the EAACI Congress in Glasgow, Peter Schmid-Grendelmeier was honored with the EAACI Clinical Fellow Award 2025. He is the first Dermatologist to receive this prestigious recognition.

We are proud to have Peter Schmid-Grendelmeier as part of our CK-CARE team and to benefit from his outstanding scientific work and extensive expertise. We warmly congratulate him on this well-deserved award!

Atopic Dermatitis and Cardiovascular Disease

23. May 2025

Atopic Dermatitis and Cardiovascular Disease – a deeper connection?
As part of our ongoing commitment to advancing the understanding of chronic inflammatory diseases, we at CK-CARE are proud to share the results of a newly published study in *Allergy* from our multicenter ProRaD research initiative.
Read the full publication: https://doi.org/10.1111/all.16588

20th CK-CARE Team Meeting 2025

27. February 2025

The 20th CK-CARE Team Meeting took place on 24 and 25 February 2025 under the motto ‘Embracing the concept of data analysis to further personalised patient care’. The aim of the meeting was to develop innovative ideas and prepare a draft publication for the CK-CARE Scientific Board based on the data from the CK-CARE registry and biobank. The event began with an informative presentation of the data from the CK-CARE repository and the biobank, which provided the framework for intensive group work. The participants were divided into four teams: Team 1, 2 and 3 chose the topic according to their personal interest based on the available data from the CKC repository and the biobank, while team 4 focused on science communication for the NIA app. The day was rounded off with a guided tour of the historic Fuggerei in Augsburg followed by a tapas dinner at the Tafeldecker restaurant, which provided space for lively discussions. On Tuesday, each group presented their idea in a 3-minute ‘Scientific Paper Pitch’ to the critical members of the ‘CK-CARE Scientific Board-lion’s den’.

(Copyright Image: Samuel Tschaffon, UK Augsburg)

Global Allergy Forum 2022

19. September 2024

The 4th Davos Declaration: A Milestone for Atopic Dermatitis Patient Care

During the last Global Allergy Forum (GAF) key opinion leaders from science, medicine and industry met in Davos to discuss the current state of the art of patient care in atopic dermatitis (AD) and proposed new strategies for its improvement. The thinktank addressed the high prevalence of AD and strategized methods to advance research, diagnostics, management and prevention. The findings are now published as «Navigating the Evolving Landscape of Atopic Dermatitis: Challenges and Future Opportunities: the 4th Davos Declaration».