From October 16–18, 2025, more than 70 international experts gathered at the Medicine Campus Davos for the 5th Global Allergy Forum. Under the theme “Allergy and Environment – Loss of Balance and Ways to Restore It”, participants explored how environmental factors drive the rise of allergic diseases and discussed innovative strategies to restore immune balance. Key topics included nutrition and environmental exposures, the role of skin and mucosal barriers, psychoneuroimmunology, and the use of artificial intelligence in allergy research. The forum’s conclusions will be summarized in the upcoming “Davos Declaration.”

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“New and advanced treatments for atopic dermatitis (AD) are moving beyond just managing symptoms. For some patients, these therapies can modify the disease itself, potentially leading to long-term remission (“deep remission”) even after stopping medication. This new treatment goal is called “disease modification.” The aim is to fundamentally change the course of AD and its related health conditions, offering transformative and lasting relief. However, optimal measurement of deep remission remains a key challenge for clinicians, researchers, regulators, and ultimately the payers. Our recent publication in Allergy discussing the Atopic Dermatitis Disease Activity Index (ADDAI), a composite tool to help determine if a treatment has successfully achieved true disease modification, helping doctors and patients know if the right treatment approach has been found. (link to publication).

We are proud to share our latest paper published in Nutrients by the CK-CARE Consortium:

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This study, conducted within the CARE birth cohort, provides new insights into how maternal nutrition during pregnancy influences the development of atopic dermatitis in early childhood.

Key findings:

• A Mediterranean diet during pregnancy significantly reduces the risk of early childhood AD.
• Greater dietary diversity is also associated with a lower AD risk.
• In contrast, frequent red meat consumption correlates with persistent AD symptoms.

These results underscore the importance of nutritional patterns—not just individual nutrients—in shaping immune development and allergic disease susceptibility.

Congratulations to the research team as well as all members of the CK-CARE study group and our international collaborators.

At CK-CARE, we are committed to advancing prevention strategies for allergic diseases through interdisciplinary and translational research. This study highlights the critical window of opportunity during pregnancy for long-term immune health.

On June 13, 2025, at the EAACI Congress in Glasgow, Peter Schmid-Grendelmeier was honored with the EAACI Clinical Fellow Award 2025. He is the first Dermatologist to receive this prestigious recognition.

We are proud to have Peter Schmid-Grendelmeier as part of our CK-CARE team and to benefit from his outstanding scientific work and extensive expertise. We warmly congratulate him on this well-deserved award!